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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DENND4C All Species: 13.33
Human Site: S1365 Identified Species: 48.89
UniProt: Q5VZ89 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VZ89 NP_060395.4 1673 186857 S1365 I I T E E T G S A V E P S D E
Chimpanzee Pan troglodytes XP_520506 1889 209618 S1581 I I T E E T G S A V E P S D E
Rhesus Macaque Macaca mulatta XP_001101451 1897 211288 S1589 T I T E E T G S A V E P S D E
Dog Lupus familis XP_852024 1908 212109 S1600 T I T E E T T S A V E S S D E
Cat Felis silvestris
Mouse Mus musculus Q3U1Y4 1499 164722 R1204 S V Q T L D S R P S A P S P K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424821 1830 204859 S1521 S H T I A E E S S S A A E Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919990 1942 214159 M1632 D S K S P V E M P V A Q T G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 85.4 80.4 N.A. 20.7 N.A. N.A. N.A. 66.5 N.A. 49.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 82.4 86.1 83.5 N.A. 36.2 N.A. N.A. N.A. 75.6 N.A. 62.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 13.3 N.A. N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 26.6 N.A. N.A. N.A. 20 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 58 0 43 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 15 0 0 0 0 0 0 0 58 0 % D
% Glu: 0 0 0 58 58 15 29 0 0 0 58 0 15 0 58 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 43 0 0 0 0 0 0 15 0 % G
% His: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 29 58 0 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 15 0 0 0 29 0 0 58 0 15 0 % P
% Gln: 0 0 15 0 0 0 0 0 0 0 0 15 0 15 0 % Q
% Arg: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % R
% Ser: 29 15 0 15 0 0 15 72 15 29 0 15 72 0 15 % S
% Thr: 29 0 72 15 0 58 15 0 0 0 0 0 15 0 15 % T
% Val: 0 15 0 0 0 15 0 0 0 72 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _